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Subject Area

Anaesthesia and Surgical Intensive Care

Article Type

Review Article

Abstract

Background: Fluid overload in septic shock patients is linked to higher morbidity and mortality. After the stabilization phase, fluid restriction may not result in the resolution of tissue edema. Active deresuscitation refers to the use of diuretics or ultrafiltration for the removal of excess fluids. Objectives: This review explores the current practices applied for the active deresuscitation strategies after stabilization of septic shock patients.  Search strategy: A literature search was performed through the following databases: Medline, PubMed, Google Scholar, Web of Science, and Scopus for relevant studies from 2015 to January 2026. Selection criteria:  The selected articles included clinical trials, observational studies, and case series, with exclusion of case reports and studies involving animals or the pediatric population. Results: The primary search retrieved 98 studies. After exclusion of duplicates and ineligible studies, 10 articles were included in the final review. Conclusions: Implementation of active deresuscitation after recovery from septic shock allows early removal of excess fluids and offers a potential beneficial influence on patients' outcomes. Further studies are required to solve conflicts regarding the timing, indication, and extent of active fluid removal.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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