Serum Resistin Levels in Patients with Acne Vulgaris and It's Correlation with Disease Severity

Marwa M. Lasheen, Dermatology, Andrology and STDs Department, Faculty of Medicine, Mansoura University, Mansoura, EgyptFollow
Magdy A. ElSohafy, Dermatology, Andrology and STDs Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt
Gehad M. El Mazny, Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt
Manar A. Hassan, Dermatology, Andrology and STDs Department, Faculty of Medicine, Mansoura University, Mansoura, EgyptFollow

Subject Area

Dermatology

Article Type

Original Study

Abstract

Background: Acne is a condition characterized by inflammation of the pilosebaceous unit, and resistin—an inflammatory hormone may contribute to its pathogenesis, as studies show altered serum levels in acne patients. This work aimed to evaluate serum resistin levels in acne vulgaris patients and its association with disease severity. Methods: This Case control study involved 46 individuals had acne vulgaris, ranged in age from 18 to 35, free of systemic medication for the three months or topical treatment for the last month and 46 apparently healthy age and sex matched subjects. The patients were then split into two categories: Cases (n = 46) and Control (n = 46). All patients were subjected to serum resistin measurements. Results: A significant correlation (P0.05). Conclusions: Problems with acne vulgaris are prevalent among middle-aged adults and teenagers, and serum resistin shows strong potential as a diagnostic biomarker, effectively distinguishing affected patients from healthy controls.

Recommended Citation

Lasheen, Marwa M.; ElSohafy, Magdy A.; Mazny, Gehad M. El; and Hassan, Manar A. (2025) "Serum Resistin Levels in Patients with Acne Vulgaris and It's Correlation with Disease Severity," Mansoura Medical Journal: Vol. 56 : Iss. 2 , Article 9.
Available at: https://doi.org/10.58775/2735-3990.1504