Article Type
Original Study
Abstract
In rheumatoid arthritis, the build up of fibrin within the joint may be responsible for some form of chronic inflammation and joint manifestations including pannus formation and polymorph induced cartilage destruction (Belch et al., 1984). An elevated plasma fibrinogen is a well recognised feature of active rheumatoid arthritis (RA), and the presence of large amount of fibrin in the synovial fluid and membrane is also well documented in this disease (Back Anderson & Gormsen, 1976). Defective fibrinolytic activity has been demonstrated in many inflammatory conditions such as: rheumatoid arthritis (Belch et al., 1984), systemic fupus erythema to sus (SUE) {Chu et al., 1988) and Behcet's syndrome (Guntifie, 1973). However, the exact clinical implication of defective fibrinolytic activity in various rheumatic conditions is still as yet a controversy. Therefore, we have decided to study the fibrinolytic activity of the peripheral blood in patients with RA in relation to some clinical and laboratory manifestations in those patients.
Recommended Citation
Sultan, W. A.; Youssef, A. A.; and Ghoneim, H. R.
(1990)
"FIBRINOLYTIC ACTIVITY IN RHEUMATOID ARTHRITIS,"
Mansoura Medical Journal: Vol. 19
:
Iss.
1
, Article 14.
Available at:
https://doi.org/10.21608/mjmu.1990.138844
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