Article Type
Original Study
Abstract
Non-Hodgkin's lymphomas are a diverse group of tumours which show morphologically a heterogenous wide spectrum of disease complexes and often unpredictable response to treatment. Clinically they vary from fulminate conditions to chronic indolent processes (Jelliffe, 1986). According to the Working Formulation, the NHLs are grouped into three broad prognostic categories, low, intermediate and high grade diseases. Low grade NHLs are composed of three histologic subtypes by the Working Formulation: small lym-phocytic (SLL), follicular small cleaved cell (FSCL) and follicular mixed small cleaved and large cell (FML). Whereas radiotherapy is potiential-ly curative in localized disease (stage I and II), the most appropriate management of wide-spread lymphoma remains controversial. Current therapeutic modalities range from a cautious "Watch and Wait" approach, through chemotherapy of moderate intensity, to aggressive muftidrug regimens combined with total nodal irradiation (Young et al., 1988 and Port-lock, 1990). The aim of this work is review of different treatment modalities of newly diagnosed low grade NHL patients with analysis of the prognostic factors for response and survival.
Recommended Citation
El-Wehedi, G; A. Horwich, A; Sakr, H, H; El-Shahat, A, A; and EI-Awdi, M, M
(2000)
"PROGNOSTIC FACTORS IN LOW GRADE LYMPHOMA (Study of 278 Cases),"
Mansoura Medical Journal: Vol. 29
:
Iss.
1
, Article 6.
Available at:
https://doi.org/10.21608/mjmu.2000.126793
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
