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Article Type

Original Study

Abstract

This study was conducted on 40 ASA physical status I-11 outpatients who were scheduled for unilateral ESWL to evaluate the safety and effi­cacy of ketamine versus fentanyl when infused in combination with mid-azolam for sedation and analgesia. Patients were randomly allocated into two equal groups according to the study drug used ketamine group and fentanyl group. Midazolam 1-3 mg was given to all patients IV to relieve anxiety. Heart rate, systolic and dia-stolic blood pressure, respiratory rate and oxygen saturation were recorded every 5 min during ESWL procedure. Involuntary movements, respiratory upsets, episodes of desaturation, nausea / vomiting and complaints of pain were also recorded. Although both drug regimens allowed the maxi­mal number of shock waves and en­ergy levels, ketamine infusion provid- ed superior intraoperative cardiores-piratory stability. However it was as­sociated with more disruptive move­ments during the procedure and longer recovery times. Incidence of-common postoperative side effects (nausea, vomiting, dizziness, confu­sion) did not differ significantly be­tween the two groups. From the re­sults of the study we can conclude that lithotripsy can be satisfactorily performed by employing ketamine in­fusion in combination with mrdazolam for sedation and analgesia. This study was conducted on 40 ASA physical status I-11 outpatients who were scheduled for unilateral ESWL to evaluate the safety and effi­cacy of ketamine versus fentanyl when infused in combination with mid-azolam for sedation and analgesia. Patients were randomly allocated into two equal groups according to the study drug used ketamine group and fentanyl group. Midazolam 1-3 mg was given to all patients IV to relieve anxiety. Heart rate, systolic and dia-stolic blood pressure, respiratory rate and oxygen saturation were recorded every 5 min during ESWL procedure. Involuntary movements, respiratory upsets, episodes of desaturation, nausea / vomiting and complaints of pain were also recorded. Although both drug regimens allowed the maxi­mal number of shock waves and en­ergy levels, ketamine infusion provid- ed superior intraoperative cardiores-piratory stability. However it was as­sociated with more disruptive move­ments during the procedure and longer recovery times. Incidence of-common postoperative side effects (nausea, vomiting, dizziness, confu­sion) did not differ significantly be­tween the two groups. From the re­sults of the study we can conclude that lithotripsy can be satisfactorily performed by employing ketamine in­fusion in combination with mrdazolam for sedation and analgesia.

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Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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