Article Type
Original Study
Abstract
Myasthenia gravis (MG) is a known potentially debilitating, and life threatening disease, for which thy-mectomy is considered the optimal treatment. Ten to twenty percent of patients are found to have thymomas, which reflects its presence in a different clinical presentation, more severe disease state and worse response to surgery. The aim of this study is to compare between thymomatous and nonthymomatous MG. The study included 63 patients of myasthenai gravis for whom thymectomy was performed. They were divided into two groups, Group 1 of 51 patients with nonthymomatous MG, and Group 2 of 12 patients with thymomatous MG. The mean age of group 1 was 27.6 years while that for group 2 was 48.3 years (P.value 0.003). The female to male ratio in group 1 was 2.9:1 and that of group 2 was 1:2 (P.value 0.001). There was no difference in the symptomatology or duration of illness between the two groups. Group 2 patients needed more medications than those of group 1 (P.value 0.01).Group 1 patients were mainly in a moderately severe disease grade (mainly grade IIA , IIB , and III) while those of group 2 were in an advanced disease grade (IIB, III, and IV) (P.value 0.001).Extended thymectomy was performed for ail the patients with good prognosis in group 1 patients (51% remission , 45.1% benefited, and 3.9% unchanged ) and worse prognosis in group 2 patients (no remission, 50% benefited, and 50% unchanged or worse) (P.value 0.001). We concluded that thymomatous MG is markedly different from nonthymomatous MG with older age presentation, more in men , appears in an
Recommended Citation
Mowafy, Abed. A.
(2001)
"THYMOMATOUS VERSUS NONTHYMOMATOUS MYASTHEN1A GRAVIS, A COMPARATIVE STUDY,"
Mansoura Medical Journal: Vol. 30
:
Iss.
1
, Article 10.
Available at:
https://doi.org/10.21608/mjmu.2001.127007
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
