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Article Type

Original Study

Abstract

Background: The cause of chest discomfort in patients with primary mi­tral valve prolapse (MVP) remains un­known. Aim: our aim was to determine prospectively the incidence of esoph-ageal disorders and abnormal re­sponses to esophageal acid infusions in patients with primary MVP with and without chest pain, Patients and Methods: 28 patients with primary MVP diagnosed by echo-cardiography underwent esophageal motility study and provocative testing with acid infusion. Ten healthy sub­jects served as control group; they also underwent the same studies. Results: Esophageal manometry revealed esophageal disorders in 14 patients: diffuse esophageal spasm in 9 patients, hypotensive lower esopha­geal sphincter (LES) in 4, hyperten­sive LES in 3, nonspecific motor dis­orders in 2 and no patient with nutcracker esophagus. Acid infusion tests (Bernstein tests) evoked typical chest discomfort in 11 of 28; most of them were in group 111 with severe MVP, on the other hand, acid infusion test evoked chest discomfort in only one of 10 control subjects. Conclusion: Esophageal disorders were common and may account for chest discomfort in some patients with primary MVP and persistent chest pain syndromes.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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