Article Type
Original Study
Abstract
Thrombolytic therapy, the important therapeutic agents in patients with acute myocardial infarction has been reported to be associated with significant early onset protenuria. The aim of this study was to determine whether streptokinase therapy is associated with changes in renal function (both glomerular and tubular) in excess of that expected in an acute vascular event; and the possible path-ogenesis of any observed changes among patients with uncomplicated acute myocardial infarction. Our work comprised 30 patients with uncomplicated acute myocardial infarction selected from coronary care unit Mansoura Emergency Hospital. They comprised 15 patients who received streptokinase therapy {thrombolytic group) and 15 patients who did not receive streptokinase therapy (non thrombolytic group). Laboratory tests reflecting both glomerular functions {serum create-nine createnine clearance and urinary albumin excretion) and tubular functions {serum and urinary B2 micro-globulin) were estimated for every patient on admission; 24 hours after initiation of therapy as well as on the 7th day of therapy. The results showed: A) Non significant changes in renal functions among patients with acute myocardial infarction not receiving thrombolytic therapy
Recommended Citation
Mahfouz, Esam M.; Mohamed, Kefaya S.; El-Safty, Eman; and Omer, Ashraf A.
(2001)
"STUDY OF RENAL FUNCTION AFTER THROMBOLYTIC THERAPY IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION,"
Mansoura Medical Journal: Vol. 30
:
Iss.
2
, Article 10.
Available at:
https://doi.org/10.21608/mjmu.2001.127036
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
