Article Type
Article
Abstract
This retrospective study was carried out to evaluate the results of treatment modalities and to identify the prognostic factors affecting survival (OAS) and disease free survival (DPS) of 116 laryngeal cancer patients treated and followed up in Clinical Oncology and Nuclear Medicine and ENT departments, Mansoura University Hospital during the period 1990-1999 inclusive. Laryngeal carcinoma represented 0.8% of all malignancies and 8.5% of all head and neck cancers during the period of the study. The median age of the patients was 60 years with a male to female ratio 22:1. History of smoking was found in 62.9% of cases. The main presenting symptom was hoarseness of voice (62.1%). Glottic carcinoma formed the majority of cases (44.8%). Squamous celf carcinoma was the commonest pathology (95%). Grade I was the commonest tumor grade (46.6%). Different treatment modalities were used in the management of the patients. Radiotherapy was used alone in treatment of 28 patients (24.1%); surgery alone in 12 patients (10.3%); and combined surgery and radiotherapy in 70 patients (60.3%). Chemotherapy was added to either surgery or radiotherapy or both in 6 cases (5.2%). Combined modality treatment of surgery followed by radiotherapy resulted in longer OAS and better DPS. Early lesions T1-T2, NO-N1 showed better response to treatment and better OAS. DPS at 18 months was 95% for T1 lesion. Treatment of laryngea! carcinoma needs a multi-disciplinary approach to standardize treatment policies, to avoid excessive surgery for early lesions and to use organ preservation proto-
Recommended Citation
Abdel-Naby, Azza S; Yousef, Mahmoud; and El-Awadi, Mohamed M
(2002)
"EVALUATION OF TREATMENT MODAL ITIES IN LARYNGEAL CANCER,"
Mansoura Medical Journal: Vol. 31
:
Iss.
2
, Article 9.
Available at:
https://doi.org/10.21608/mjmu.2002.127104
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This work is licensed under a Creative Commons Attribution 4.0 International License.
