Article Type
Original Study
Abstract
Background : GERD is a common gastro-intestinal disorder. It is considered as chronic medical that needs long term medical treatment. Long term acid suppressive therapy, inspite of being considered safe, may result in bacterial overgrowth and secondary hypergastrinemia. The aim of this study is to evaluate the effectiveness of natural sialagogues (sugarless gum) as non-pharmacological treatment to control the pathological acid reflux. Subject and methods: 50 patients were selected from outpatient cfinic of tropical medicine department complaining of heart burn and/or epigastric pain. They were confirmed as having pathological GERD by 24 hr pH metry. All patients were subjected to: full history, thorough physical examination, ECG, and upper G.I.T en-doscopy. Ambulatory 24 hrs. esopna-gea! pH monitoring was done in the first day without using natural sialagogues and repeated in second day during using natural sialagogues. Measurement of salivary volume, ph, bicarbonate and Epidermal growth factor (EGF) before and after using natural sialagogues. The result: there was statistically significant symptomatic improvement in patients with GERD. 20% cf patients with GERD by ph metry showed normal endoscopoic findings. There were statistically significant increase in all measured parameters after chewing gum. 41% of patients who had GERD showed decrease in 24 hrs pH metry score after
Recommended Citation
Mourad, Amr; El Badrawy, El-Said; Mahmoud, Ahmad; Abo El-Magd, Yousry; and Mahdy, Sherif
(2005)
"EFFECTIVENESS OF NATURAL SIALAGOGUES IN THE TREATMENT OF PATHOLOGICAL GASTROESOPHAGEAL ACID REFLUX DISEASE (GERD),"
Mansoura Medical Journal: Vol. 34
:
Iss.
1
, Article 4.
Available at:
https://doi.org/10.21608/mjmu.2005.127754
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