ACCUMULATION OF CADMIUM AND IRON IN THE HYDROCELE FLUID OF INFERTILE MEN WITH PRIMARY VARICOCELE; A POSSIBLE ROLE IN MALE INFERTILITY

Authors

Mosaad Soliman, Departments of Surgery Mansoura Faculty of Medicine and Mansoura University Hospital, Mansoura, Egypt
Mohamed Abdel Latif, Departments of Medical Biochemistry Mansoura Faculty of Medicine and Mansoura University Hospital, Mansoura, Egypt
Yosry Mostafa, Departments of Medical Biochemistry Mansoura Faculty of Medicine and Mansoura University Hospital, Mansoura, Egypt
Hamed Yousef, Departments of Gynecology Mansoura Faculty of Medicine and Mansoura University Hospital, Mansoura, Egypt
Hosam Zaghlol, Departments of Clinical pathology Mansoura Faculty of Medicine and Mansoura University Hospital, Mansoura, Egypt

Article Type

Original Study

Abstract

Varicoceles are a common cause of male infertility, but despite data from human studies the pathophysio-logy remains unclear. Seminal plas­ma cadmium concentrations were found to be increased in infertile men. In addition, increases in blood plasma cadmium concentrations in infertile men have been associated with terat-ozoospermia. Cadmium contributes to infertility by induction of apoptosis in testicular tissue. Methods: An ejac­ulate and blood sample were collect­ed immediately before surgery fol­lowed by aspiration of hydrocele fluid from the tunica vaginalis at the time of subinguinal varicocelectomy. In each specimen, cadmium and iron levels were determined by atomic ab­sorption and the effect of hydrocele fluid on the sperm velocity was deter­mined by examining aliquots of sperms suspended in hydrocele fluid compared to those suspended in seminal plasma. Results: The cadmi­um and iron levels were higher in the hydrocele fluid than the peripheral blood in 72% and 46% of patients with bilateral varicocele respectively. Hydrocele fluid added to the sperms

Recommended Citation

Soliman, Mosaad; Abdel Latif, Mohamed; Mostafa, Yosry; Yousef, Hamed; and Zaghlol, Hosam (2006) "ACCUMULATION OF CADMIUM AND IRON IN THE HYDROCELE FLUID OF INFERTILE MEN WITH PRIMARY VARICOCELE; A POSSIBLE ROLE IN MALE INFERTILITY," Mansoura Medical Journal: Vol. 35 : Iss. 1 , Article 12.
Available at: https://doi.org/10.21608/mjmu.2006.128753

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.