Article Type
Original Study
Abstract
Background : The strikingly lower prevalence of acute coronary syndromes in pre-menopausal women than in men of similar age, then the progressive narrowing of that difference with age after menopause, suggests an important role for sex hormones and probably oxidative stress in the development of coronary artery disease. Objective : The aim of this study is to evaluate the sex hormones and ox-idant stress (malondialdehyde, which is a metabolite of lipid peroxidation) and anti-oxidants (vitamin C and E) status in postmenopausal women with stable coronary artery disease and in those with acute coronary syndromes, Subjects & Methods : This study was conducted on 40 non-hormone user postmenopausal women with coronary artery disease. They were divided into 3 groups: the 1st group (17 patients) who had an acute myo-cardial infarction, the 2nd group (10 patients) had unstable angina and the 3rd one (13 patients) had stable angina. This is in addition to 20 apparently healthy postmenopausal women of similar age. All cases and control subjects were subjected to thorough history taking, full clinical examination, routine laboratory investigations, resting echocardiography and special
Recommended Citation
Helaly, Mohamed; Daoud, Eid; Abdel Aal, Ibrahtm; Ghanem, Hosam; El-Arman, Mohammed; Mesbah, Abeer; and Arafa, Lamiaa
(2006)
"SEX HORMONES AND OXIDANT- ANTIOXIDANT STATUS IN POST-MENOPAUSAL WOMEN WITH CORONARY ARTERY DISEASE,"
Mansoura Medical Journal: Vol. 35
:
Iss.
1
, Article 5.
Available at:
https://doi.org/10.21608/mjmu.2006.128719
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This work is licensed under a Creative Commons Attribution 4.0 International License.
