Article Type
Original Study
Abstract
Background : The histologic presence of intestinal metaplasia in the esophagus is a prerequisite for the diagnosis of Barren's esophagus. Short-segment Barren's esophagus is three times more frequent than long-segment Barrett.s esophagus, with simitar risk of dysplasia and adeno-carcinoma. Our objective was to study the clinical and pathophysiologi-cal characteristics of short-segment Barrett's esophagus. Patients and Methods : Demographic informations, data on tobacco and body mass index were recorded for all patients. Before upper gastrointestinal endoscopy and esophageal manometry, all patients completed a validated gastroesophageal reflux disease questionnaire. The diagnosis of short-segment Barrett's esophagus was based on the presence of columnar-appearing mucosa in the distal 3cm of the esophagus, with confirmation by demonstration of intestinal metaplasia in biopsy specimens. Results : The studied patients included group 1 (11 patients having short-segment Barrett's esophagus) and group 2 (29 patients suffering gastroesophageal reflux disease without Barrett.s esophagus). In group !, smoking was found in 4 patients, ul-cerogenic drug intake in 4 patients, bad dietary habits in 6 patients and obesity in 5 patients. The relative risk for obesity (1.73), for drugs (1.5)
Recommended Citation
El-Gamal, Salah; Eldesoky, Ayman; Zakaria, Yahia; Zalata, Khaled; and Mohamed, Moamer
(2008)
"CLINICAL AND PATHOPHYSIOLOGICAL CHARAC- TERISTICS OF SHORT-SEGMENT BARRETTS ESOPHAGUS,"
Mansoura Medical Journal: Vol. 37
:
Iss.
1
, Article 12.
Available at:
https://doi.org/10.21608/mjmu.2008.129192
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