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Article Type

Original Study

Abstract

Microfilaments and intermediate filaments (Ifs) represent an important components of the cytoskeleton. In mammals including rats, peritubular myoid cells (PMCs) contain alpha smooth muscle actin (ct-SMA) micro-filaments, while sertoli cells contain intermediate filaments vimentin. Pre­vious studies mentioned some as­pects about the distribution of these filaments in these cells, however little was mentioned about the changes in their distribution during postnatal (p.n) development. In the present study, immunohisto-chemical methods were used to de­tect the changes in distribution of a-SMA in PMCs and vimentin in sertoli cells during postnatal development of rat testis (one day,7 days,14 days,28 days.42 days and 56 days) a- SMA immune reaction was seen early from the 1 st day of p.n age in few PMCs. On p.n day 7. there was increase in PMCs exhibiting +ve a-SMA immune reaction. This reaction was well established around the whole circumference of the seminifer­ous tubules on p.n day 14 and the adult distribution pattern was seen on p.n day 28. Intermediate filaments (Ifs) vimen­tin were mainly observed at the basal nuclear region of few sertoli cells on p.n day 7 and the first appearance in supranuclear or apical region was on p.n day 14.

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Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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