EFFECT OF ANASTOMOTIC LENGTH ON THE DEVELOPMENT OF INTIMAL HYPERPLASIA IN THE DISTAL ANASTOMOSIS OF BYPASS GRAFT.

Authors

Mohamed Elsharawy, Department of Surgery, Faculty of Medicine, King Faisal University, Saudi Arabia

Article Type

Original Study

Abstract

Many hemodynamic factors have been shown to be associated with in­creased intimal hyperplasia at the dis­tal anastomosis of arterial bypass graft. However, the relationship be­tween the length of anastomosis and development of such complication has not been studied before. The aim of this study is to assess this relation­ship at the distal anastomosis with Dacron graft. Material and Methods : lleo-femoral bypasses were performed in 10 German shepherd dogs using 6-mm Dacron grafts. In accordance with preoperative randomization to in­dividual animal legs, distal anasto- moses were reconstructed applying four different groups (A, B, C and D) depending on the length of the arteri-otomy: 3.0, 3.5, 4.0 and 4.5 times the internal diameter of the artery respec­tively. The vessels were harvested 6 months after the operation and speci­mens were processed for histological study. Quantitative analysis was per­formed to assess the extent of intimal hyperplasia at three zones (heel, toe and mid-zone of the arterial bed) of the distal anastomosis. Results: Sixteen arterial bypasses were included in this study. Light mi­croscopy revealed evidence of intimal hyperplasia in the four groups. Quan­titative analysis showed significant MANSOURA MEDICAL JOURNAL

Recommended Citation

Elsharawy, Mohamed (2009) "EFFECT OF ANASTOMOTIC LENGTH ON THE DEVELOPMENT OF INTIMAL HYPERPLASIA IN THE DISTAL ANASTOMOSIS OF BYPASS GRAFT.," Mansoura Medical Journal: Vol. 38 : Iss. 1 , Article 1.
Available at: https://doi.org/10.21608/mjmu.2009.130321

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.