Article Type

Original Study


Rotavirus is responsible for a significantgastrointestinal disease primarilyin children less than 5 yearsofage worldwide causing massivemorbidityand mortality. This studyaimedto identify the proportion ofchildrenwith acute gastroenteritis infectedwith rotavirus through systematicsampling over a 1-year period inatertiary care hospital, MansouraUniversityChildren’s Hospital - Mansoura-EgyptPatients and MethodsThis study included all hospital-ized children aged less than 5 yearswho presented with acute waterydiarrhea. Collected stool sampleswere tested for the presence of rotavirus using an ELISA kit. ResultsOut of 385 stool samples, rotavi-rus antigen was detected in the stoolsamples of 144 (37.4%), of which 74(45.9%) samples were from infantsin the age group of 0–12 months. Feverwas found to be significantlymorefrequent among children withrotaviruspositive samples [86.5%vs.55.7%, P=0.02]. The same wasfoundwith vomiting as it was morefrequentamong children with rotaviruspositive samples [80% vs.67.7%,P=0.05]. Severe dehydrationwassignificantly more common inpatientswith rotavirus infection[31.9%vs. 18%, P=0.02], while mildandmoderate dehydration did not show the same level of significance[17% vs. 22.5, P=0.42] and [51% vs.59.4%, P=0.74] respectively. Rotaviruspositive cases aged less thanoneyear were found to present withasevere degree of dehydration 34(45.9%)while moderate degree ofdehydrationwas most frequently presentedamong other age groups indicatingthat the younger the age themorethe severity of symptoms ofrotavirusinfection.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.