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Corresponding Author

Abd El-Ghany, Mohammed

Subject Area

Endocrinology

Article Type

Original Study

Abstract

Background: Diabetes prevalence increases with age. In 2019, IDF estimated the number of diabetic people above 65 years is 135.6 million (19.3%), expected to be 276.2 million in 2045, leading to a significant increase in the diabetes population of aging societies in the next 25 years and the inevitable public health, and economic challenges this will bring. Aim: To evaluate how clinical characteristics, degree of glycemic control, and presence of chronic complications differ between older and younger T2DM subjects. Methods: A cross-sectional study that includes 200 T2DM participants were classified into 2 groups. Group A includes 100 subjects aged < 65years. Group B includes 100 subjects aged > 65years. Detailed clinical history was taken. Also, HbA1c was measured. Results: Glycemic control was achieved in 46% of older diabetics vs. 37% of younger diabetics (HbA1c 7.2 vs 7.8), but statistically insignificant. Univariate analysis revealed non-obese vs. obese, DBP ≤85 vs >85, TC level ≤158 mg/dl vs >158, and TG level ≤129 mg/dl vs. >129 were statistically significant predictors of diabetic control. Multivariate analysis revealed non-obese state (OR=2.2) and DBP≤85mmHg (OR=2.1) were statistically significant independent predictors of the likelihood of diabetic control. The best cut-off values for DBP, TC, TG were 85, 158, 129, the AUC were 0.593 (p=0.016), 0.579 (p=0.053), 0.574 (p=0.072) respectively, to identify the optimal levels for the prediction of a controlled diabetic state. Conclusion: The degree of glycemic control and cardiovascular risk factors were better in the elderly T2DM subjects, however, the complications were more common among them.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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