Impact of COVID - 19 Pandemic on The Clinical Course of Inflammatory Bowel Disease in Egyptian Tertiary Centers

Alaa Alsawak, Gastroenterology and Hepatology Unit, Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt
Omar AbdAllah, Hepatology and Gastroenterology Unit, Department of Internal Medicine, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt
Ali Madian, Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Assiut, Egypt
Hassan Atalla, Hepatology and Gastroenterology Unit, Department of Internal Medicine, Mansoura Faculty of Medicine, Mansoura University, Mansoura, EgyptFollow
Ramadan Eldamarawy, Gastroenterology and Hepatology Unit, Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt
Ahmed Eliwa, Gastroenterology and Hepatology Unit, Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt
Ahmed Khamiss, Gastroenterology and Hepatology Unit, Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt
Ashraf El Sharkawy, Gastroenterology and Hepatology Unit, Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt
Sadek Mostafa, Gastroenterology and Hepatology Unit, Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt
Alshimaa Alaboudy, Department of Tropical Medicine and Gastroenterology, Sohag Faculty of Medicine, Sohag University, Sohag, Egypt
Maha M. Maher, Hepatology and Gastroenterology Unit, Department of Internal Medicine, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt
Ashraf Elbahrawy, Gastroenterology and Hepatology Unit, Department of Internal Medicine, Al-Azhar School of Medicine, Al-Azhar University, Cairo, Egypt

Corresponding Author

Hassan Atalla

Subject Area

Internal Medicine

Article Type

Original Study

Abstract

Background/Aim: The coronavirus disease 2019 (Covid-19) pandemic have a major impact on the clinical course of chronic diseases including inflammatory bowel disease (IBD). In the current study we aimed to evaluate the clinical relapse and worsening of IBD activity during Covid-19 pandemic.

Methods: 125 patients included and followed for one year. Of them, 98 and 27 patients had inactive and active IBD before the study, respectively. The clinical activity of IBD assessed by Crohn’s disease activity index (CDAI) and simplified colitis clinical activity index (SCCAI). Severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) infection detected by real-time polymerase chain reaction.

Results: The mean age of included patients was 34.3 ±11.2 years, of them 54(43.2%) were males. 43(34.4%) and 82(65.6%) patients had Crohn’s disease (CD) and ulcerative colitis (UC), respectively. 46 (47%) patients developed clinical relapse within one year. Of them 22 (48%) patients were not adherent to treatment during the pandemic (P ≤ 0.05). 33.3% of patients with active IBD before the study, had worsened activity during the pandemic. The incidence of SARS-CoV-2 infection among included patients was 8 % (n=10).

Conclusion: The majority of relapsed IBD patients were not adherent to treatment due to the fear of Covid-19 infection.

Recommended Citation

Alsawak, Alaa; AbdAllah, Omar; Madian, Ali; Atalla, Hassan; Eldamarawy, Ramadan; Eliwa, Ahmed; Khamiss, Ahmed; Sharkawy, Ashraf El; Mostafa, Sadek; Alaboudy, Alshimaa; Maher, Maha M.; and Elbahrawy, Ashraf (2023) "Impact of COVID - 19 Pandemic on The Clinical Course of Inflammatory Bowel Disease in Egyptian Tertiary Centers," Mansoura Medical Journal: Vol. 52 : Iss. 1 , Article 2.
Available at: https://doi.org/10.58775/2735-3990.1371