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Corresponding Author

Hoda M. Sobh

Subject Area

Cardiology

Article Type

Original Study

Abstract

Background: The main target of treatment of STEMI is to restore coronary blood flow and maintain myocardial perfusion. Several tools including electrocardiographic and coronary angiographic parameters are used to assess myocardial reperfusion. Fragmented QRS is associated with increased adverse cardiovascular events, it was proved to bea marker of ventricular dysfunction and poor prognosis in STEMI. Aim of the work : To study the relation between QRS fragmentations and the degree of myocardial reperfusion in patients with STEMI treated with either fibrinolytic therapy or primary percutaneous coronary interventions (1ry PCI). Patients and methods: 100 subjects admitted with first attack of STEMI were included. Twelve leads ECGs were evaluated for QRS morphology, patients were randomized in two groups according to presence or absence of QRS fragmentation, F-QRS group included 35 patients and NF-QRS group included 65 patients. The following parameters were used to assess the success of coronary reperfusion; ST segment resolution, TIMI score, MBG score and cardiac enzymes resolution. Results: ST segment resolution score was significantly higher among NF-QRS t. NFQRS group had better MBG and TIMI scores compared to patients with F-QRS group. F-QRS was significantly associated with lower EF and higher Klipp score. CKmb was significantly higher among F-QRS group. Complications were significantly higher among patients with F-QRS. Conclusion: QRS fragmentation can be a reliable predictor of coronary reperfusion in patients with acute STEMI treated with primary PCI or thrombolytic therapy.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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