Subject Area

Obstetrics & Gynaecology

Article Type

Original Study


Background: Hepatitis C has the highest frequency in Egypt, with 14.7 percent of the population affected between the ages of 15 and 49, according to the World Health Organization. Hepatitis C virus antibodies have been detected in 12.2% of women and 17.4% of men. Patients and Methods: This research was carried out in Mansoura University Hospital, Mansoura, Egypt. All participants (90 cases) in this study provided written informed consent to participate and were separated into 2 groups, the first group (group A) & the second group (group B). Women in group A (45 cases) were hepatitis C virus antibodies tested positive underwent PCR to be confirmed, while group B (45 cases) were controlled Group with hepatitis C virus antibodies tested negative. Results: There was no significance between studied groups regarding age, BMI, parity, gravidity, abortion. There were significant negative correlations were observed between AMH and HCV infection, as well as between AFC and HCV infection. Differences in AMH and AFC were also statistically significant across the groups. HCV PCR was inversely related to both AMH and AFC. Conclusion: The hepatitis C virus is a potential risk factor for infertility since it can hinder a woman's ability to reproduce by lowering ovarian reserve. It can be passed from mother to child and from mother to partner, posing risks to both the developing fetus and the newborn. There is a lot of room for new research into the effects of viruses because we just don't know enough about them yet.

Keywords: hepatitis C, AFC, AMH, ovarian reserve, Infertility.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.