Subject Area
Chest medicine
Article Type
Original Study
Abstract
Background: Exposure to environmental tobacco smoke (ETS) is associated with several medical diseases especially allergy, but little is known about the effects of cigarette smoking on allergen immunotherapy response. Aim: This study aims to explore any association between cigarette smoking and response to allergen immunotherapy in patients with allergic airway disorders. Patients and methods: The study was conducted on patients with allergic airway disorders who received subcutaneous immunotherapy. All patients were assessed as regard smoking history including pack-year index and dependence, symptoms and medication scores. Patients’ demographic and clinical data were collected. A statistical analysis was then performed. Results: A total of 54 patients were enrolled 48 males (88.9%) and 6 females (11.1%), with mean age of 30.6 ±12 years. Coincidence of Allergic rhinitis & bronchial asthma was the most frequent in 23 patients (42.6%). Non-smoker patients were the most frequent representing 63%, followed by current smokers in 29.6%. Symptom and medication scores in current smokers were highly significant better after Allergen Immunotherapy (AIT) (P =0.001, 0.005 respectively), ex-smoker showed significant improvement as regard symptoms score (P =0.05), but with no significant improvement as regard medication score (P =0.06). Among non-smokers, there was a highly significant improvement in both symptom and medication scores after AIT (P =
Recommended Citation
Abdelwahab, Heba Wagih; Bakeer, Mostafa; and Fouda, Ahmed Mohamed
(2023)
"Effectiveness of allergen immunotherapy in cigarette smokers with allergic airway disorders,"
Mansoura Medical Journal: Vol. 52
:
Iss.
3
, Article 5.
Available at:
https://doi.org/10.58775/2735-3990.1398
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This work is licensed under a Creative Commons Attribution 4.0 International License.
