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Corresponding Author

Dalia Abdellateif Abdelghany

Subject Area

Chest medicine

Article Type

Original Study

Abstract

Background: There is a significant impact on morbidity, mortality, and quality of life due to chronic obstructive pulmonary disease exacerbations. Individuals with acute exacerbation of chronic obstructive pulmonary disease had considerably higher mean serum procalcitonin levels (PCT) compared to individuals with stable chronic obstructive pulmonary disease, according to previous investigations. Objective: This study aimed to assess whether procalcitonin levels were associated with the severity of exacerbations in patients with chronic obstructive pulmonary disease. Methods: thirty-nine patients who were suffering from an acute exacerbation of chronic obstructive pulmonary disease were included. Included patients were classified as having either no respiratory failure, an acute respiratory failure that is not life-threatening, or life-threatening respiratory. Serum procalcitonin level was measured. Results: procalcitonin serum levels were not substantially associated with the severity of exacerbation in studied patients (p = 0.4). There was no correlation between procalcitonin level and pack year index, mMRC, CAT, exacerbation history, exacerbation severity, respiratory rate, or pCO2 level. Conclusion: The results of our research proved a non-significant association between PCT level and exacerbation severity of COPD patients.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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