Subject Area
Anaesthesia and Surgical Intensive Care
Article Type
Original Study
Abstract
Background: Opioid-free anaesthesia is becoming a favored strategy among anesthetists. This study aims to compare continuous epidural fentanyl infusion with intrathecal bolus of bupivacaine-dexmedetomidine, which is a low-cost analgesic technique with efficient intraoperative hemodynamic stability, postoperative analgesia, and fewer opioid induced drawbacks in urinary bladder diversion surgery.
Patient and Methods: Our randomized prospective comparative study involved 34 patients prepared for urinary bladder diversion surgery. Patients were distributed into two equivalent groups; group A received continuous epidural infusion of bupivacaine-fentanyl; and group B received intrathecal bolus bupivacaine-dexmedetomidine.
Results: Intraoperatively, Heart rate showed a significant decrease at 2 h in group B (71.82±8.76 vs 79.41±12.56) (P=.049) in compared to group A. Mean blood pressure displayed a significant decrease in group B than in group A at 1h, 1.5h, 2h , 2.5h and at 3h (P
Conclusion: Opioid-free anesthesia using intrathecal dexmedetomidine is an efficient harmless strategy that allows better control of sensory and motor block level, provides hemodynamic stability and avoids cumulative opioid induced complications. It can be used as an alternate option to continuous epidural anesthesia in patients undergoing prolonged urinary bladder diversion surgery.
Recommended Citation
Ghanem, Mohamed A; Saied, Mostafa MA; Adly, Hanan; and Badr, May E
(2024)
"Opioid-Free Anaesthesia During Prolonged Orthotopic Urinary Bladder Diversion Surgery: A Prospective Randomized Comparative Study,"
Mansoura Medical Journal: Vol. 53
:
Iss.
2
, Article 8.
Available at:
https://doi.org/10.58775/2735-3990.1422
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
