Subject Area
Anaesthesia and Surgical Intensive Care
Article Type
Article
Abstract
Background: Numerous medications have been added to spinal anesthetic over the years in order to speed up its onset, shorten the time until the surgical incision, increase its duration, and offer sufficient postoperative analgesia. Objective: This study suggests that dexmedetomidine is superior than nalbuphine as an adjuvant to intrathecal local anesthetic for the duration of post-operative analgesia in lower extremity orthopedic surgical procedures. Patients and Methods: 60 patients underwent orthopedic lower extremity procedures were split into one of three groups at random: Bupivacaine, Bupivacaine- Dexmedetomidine (BD), or Bupivacaine-Nalbuphine (BN). The principal outcome was the duration of post-operative analgesia. The secondary outcomes were the associated hemodynamic changes, postoperative pain score, total amount of postoperative analgesia required, total amount of atropine and ephedrine needed to keep hemodynamic stability and any complications. Results: Group BD had a significantly longer duration of analgesia and less total analgesics consumption than group B and BN within the first 24 hours after procedure. Conclusions: Dexmedetomidine is a great adjuvant to local anesthetics when administered intrathecally for lower extremity surgery.
Recommended Citation
Oraby, Mohamed Aly El; Hafez, Amira; Moawad, Hazem E; Trabea, Gihan A; and Salim, Maha Ahmed Abo-Zeid
(2025)
"Dexmedetomidine versus Nalbuphine as an adjuvant to intrathecal Bupivacaine in lower extremity surgeries,"
Mansoura Medical Journal: Vol. 54
:
Iss.
2
, Article 4.
Available at:
https://doi.org/10.58775/2735-3990.1447
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This work is licensed under a Creative Commons Attribution 4.0 International License.
