Subject Area
Physical Medicine, Rheumatology, and Rehabilitation
Article Type
Original Study
Abstract
Background The role of vitamin D in the pathogenesis of rheumatoid arthritis is controversial. This study aims to assess the relation between vitamin D level and rheumatoid arthritis disease activity. Patients and methods This study was conducted on 80 rheumatoid arthritis (RA) patients beside 40 healthy persons. Vitamin D level was assessed in all participants. Rheumatoid activity was assessed using DAS28 (disease activity score). RA patients were classified according to DAS 28 into two groups: active group and remission group. Results The median for vitamin D level in RA group was 23.5ng/ml. There was no statistically significant difference in serum vitamin D level between RA cases and control group (23.5ng/ml versus 25ng/ml, P 0.9). Serum vitamin D level was not significantly different between active RA patients and patients in remission (P = 0.09 respectively). There was no significant difference between patients with different levels of vitamin D as regards activity parameters. No correlation was found between vitamin D level and rheumatoid activity. Conclusion There was no difference in vitamin D level between RA patients and healthy control. Also, there was no difference in vitamin D level between RA patients with active disease and patients in remission. There was no significant association between vitamin D level and disease activity parameters.
Recommended Citation
Salem, Mohamed Hussein; Hassan, Nahed Abdullah; Abdelsalam, Adel Ibrahim; and Hamdy, Fatma
(2025)
"Relation between serum vitamin D level and disease activity in rheumatoid arthritis,"
Mansoura Medical Journal: Vol. 54
:
Iss.
4
, Article 11.
Available at:
https://doi.org/10.58775/2735-3990.1477
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
