Predictors and Outcome of Sepsis and Septic Shock Induced Acute Kidney Injury in Diabetic Patients: A Prospective Observational Study

Authors

Shrouk Essam, Department of Internal Medicine and Critical Care, Faculty of Medicine, Mansoura University, Mansoura, EgyptFollow
Rehab Shaheen Bahram Shaheen, Department of Internal Medicine and Critical Care, Faculty of Medicine, Mansoura University, Mansoura, Egypt
Rasha Mahmoud Prof., Department of Internal Medicine (Nephrology), Faculty of Medicine, Mansoura University, Mansoura, Egypt
Adel I. Abdelsalam, Department of Internal Medicine (Rheumatology and Immunology), Faculty of Medicine, Mansoura University, Mansoura, Egypt

Subject Area

Internal Medicine

Article Type

Original Study

Abstract

Background: One characteristic of sepsis is the dysregulation of the host's reaction to infection, which can result in potentially fatal organ failure.This work aimed to assess predictors and outcome of sepsis and septic shock induced acute kidney injury (AKI) in diabetic patients. Methods: This prospective observational study included diabetic patients aged over 18 years who were admitted with sepsis or septic shock in the Medical Critical Care Unit of the Specialized Medical Hospital, Mansoura University. All patients were divided into 2 groups:AKI Group (N=74): diagnosed with AKI and No AKI Group (N=26): did not develop AKI. Results: Analysis of risk factors for AKI in diabetic intensive care unit patients showed that chronic kidney disease was the strongest independent predictor (OR 59.0, p

Recommended Citation

Essam, Shrouk; Shaheen, Rehab Shaheen Bahram; Mahmoud, Rasha Prof.; and Abdelsalam, Adel I. (2026) "Predictors and Outcome of Sepsis and Septic Shock Induced Acute Kidney Injury in Diabetic Patients: A Prospective Observational Study," Mansoura Medical Journal: Vol. 55 : Iss. 2 , Article 2.
Available at: https://doi.org/10.58775/2735-3990.1514

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This work is licensed under a Creative Commons Attribution 4.0 International License.