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Subject Area

Hematology and oncology

Article Type

Original Study

Abstract

Background: Body mass index (BMI) has been suggested as an important patient-related factor influencing treatment outcomes in breast cancer. This study aimed to evaluate the association between BMI categories and clinical outcomes among patients with metastatic breast cancer (MBC).

Patients and Methods: This retrospective study included 400 patients with MBC. Clinical outcomes assessed included response to first-line treatment, treatment-related toxicity, and status at last follow-up and BMI was calculated using the Quetelet index .

Results: Patients were characterized by a high prevalence of obesity and predominantly good performance status. Disease progression following first-line treatment was the most common outcome overall (79.0%). Response patterns differed significantly across BMI categories (p

Conclusion: BMI was significantly associated with clinical outcomes in patients with metastatic breast cancer. These findings highlight the potential prognostic and clinical relevance of BMI in the metastatic setting and underscore the need for individualized treatment strategies that consider nutritional and body composition status.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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